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Restylane and Juvederm Trigger Natural Collagen Production

A study published in the Archives of Dermatology found that injecting hyaluronic acid (which is what Restylane and Juvederm are made of) into skin triggered collagen producing cells to make more collagen. The study authors injected hyaluronic acid into the forearms of volunteers and looked at what happened over time under a microscope. They found that collagen production increased significantly during the second and third months after injection. They believe that when hyaluronic acid is injected, it stretches the collagen producing cells which triggers them to make more collagen.

Since collagen lasts for many years, the results of this study imply that less Restylane or Juvederm will be needed over time to correct wrinkles as more natural collagen is produced after each injection. My own observations of patients I’ve treated in my Los Angeles Liposuction and Dermatology Center support this concept.

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